Collaborative Cross Mice Yield Genetic Modifiers for Pseudomonas aeruginosa Infection in Human Lung Disease

Human genetics influence a range of pathological and clinical phenotypes in respiratory infections; however, the contributions of disease modifiers remain underappreciated. We exploited the Collaborative Cross (CC) mouse genetic-reference population to map genetic modifiers that affect the severity...

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Detalles Bibliográficos
Autores principales: Lorè, Nicola Ivan, Sipione, Barbara, He, Gengming, Strug, Lisa J., Atamni, Hanifa J., Dorman, Alexandra, Mott, Richard, Iraqi, Fuad A., Bragonzi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064750/
https://www.ncbi.nlm.nih.gov/pubmed/32127447
http://dx.doi.org/10.1128/mBio.00097-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064750/
https://www.ncbi.nlm.nih.gov/pubmed/32127447
http://dx.doi.org/10.1128/mBio.00097-20

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