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Vaccine-Induced Th1-Type Response Protects against Invasive Group A Streptococcus Infection in the Absence of Opsonizing Antibodies

Recent global advocacy efforts have highlighted the importance of development of a vaccine against group A Streptococcus (GAS). Combo5 is a non-M protein-based vaccine that provides protection against GAS skin infection in mice and reduces the severity of pharyngitis in nonhuman primates. However, C...

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Detalles Bibliográficos
Autores principales: Rivera-Hernandez, Tania, Rhyme, Mira Syahira, Cork, Amanda J., Jones, Scott, Segui-Perez, Celia, Brunner, Livia, Richter, Johanna, Petrovsky, Nikolai, Lawrenz, Maria, Goldblatt, David, Collin, Nicolas, Walker, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752/
https://www.ncbi.nlm.nih.gov/pubmed/32156809
http://dx.doi.org/10.1128/mBio.00122-20