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RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers

During infection of human parvovirus B19 (B19V), one viral precursor mRNA (pre-mRNA) is transcribed by a single promoter and is alternatively spliced and alternatively polyadenylated. Here, we identified a novel cis-acting sequence (5′-GUA AAG CUA CGG GAC GGU-3′), intronic splicing enhancer 3 (ISE3)...

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Detalles Bibliográficos
Autores principales: Wang, Jianke, Ganaie, Safder S., Cheng, Fang, Xu, Peng, Ning, Kang, Wang, Xiaomei, Kleiboeker, Steve, Cheng, Shipeng, Qiu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064759/
https://www.ncbi.nlm.nih.gov/pubmed/32156816
http://dx.doi.org/10.1128/mBio.00192-20