Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells

In the absence of a vaccine, multidrug-resistant Neisseria gonorrhoeae has emerged as a major human health threat, and new approaches to treat gonorrhea are urgently needed. N. gonorrhoeae pili are posttranslationally modified by a glycan that terminates in a galactose. The terminal galactose is cri...

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Detalles Bibliográficos
Autores principales: Poole, Jessica, Day, Christopher J., Haselhorst, Thomas, Jen, Freda E.-C., Torres, Victor J., Edwards, Jennifer L., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064771/
https://www.ncbi.nlm.nih.gov/pubmed/32127453
http://dx.doi.org/10.1128/mBio.03046-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064771/
https://www.ncbi.nlm.nih.gov/pubmed/32127453
http://dx.doi.org/10.1128/mBio.03046-19

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