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Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells
In the absence of a vaccine, multidrug-resistant Neisseria gonorrhoeae has emerged as a major human health threat, and new approaches to treat gonorrhea are urgently needed. N. gonorrhoeae pili are posttranslationally modified by a glycan that terminates in a galactose. The terminal galactose is cri...
Autores principales: | Poole, Jessica, Day, Christopher J., Haselhorst, Thomas, Jen, Freda E.-C., Torres, Victor J., Edwards, Jennifer L., Jennings, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064771/ https://www.ncbi.nlm.nih.gov/pubmed/32127453 http://dx.doi.org/10.1128/mBio.03046-19 |
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