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The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates

The initiation of Escherichia coli chromosomal DNA replication starts with the oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The amount of ori DNA per cell directly correlates with the growth rate. During fast growth, the cell generation time is shorter than...

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Detalles Bibliográficos
Autores principales: Fernández-Coll, Llorenç, Maciag-Dorszynska, Monika, Tailor, Krishma, Vadia, Stephen, Levin, Petra Anne, Szalewska-Palasz, Agnieszka, Cashel, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064777/
https://www.ncbi.nlm.nih.gov/pubmed/32156825
http://dx.doi.org/10.1128/mBio.03223-19