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The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates
The initiation of Escherichia coli chromosomal DNA replication starts with the oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The amount of ori DNA per cell directly correlates with the growth rate. During fast growth, the cell generation time is shorter than...
Autores principales: | Fernández-Coll, Llorenç, Maciag-Dorszynska, Monika, Tailor, Krishma, Vadia, Stephen, Levin, Petra Anne, Szalewska-Palasz, Agnieszka, Cashel, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064777/ https://www.ncbi.nlm.nih.gov/pubmed/32156825 http://dx.doi.org/10.1128/mBio.03223-19 |
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