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Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport

Pyocin S5 (PyoS5) is a potent protein bacteriocin that eradicates the human pathogen Pseudomonas aeruginosa in animal infection models, but its import mechanism is poorly understood. Here, using crystallography, biophysical and biochemical analyses, and live-cell imaging, we define the entry process...

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Detalles Bibliográficos
Autores principales: Behrens, Hannah M., Lowe, Edward D., Gault, Joseph, Housden, Nicholas G., Kaminska, Renata, Weber, T. Moritz, Thompson, Catriona M. A., Mislin, Gaëtan L. A., Schalk, Isabelle J., Walker, Daniel, Robinson, Carol V., Kleanthous, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064778/
https://www.ncbi.nlm.nih.gov/pubmed/32156826
http://dx.doi.org/10.1128/mBio.03230-19