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Mycobacterium tuberculosis Reactivates HIV-1 via Exosome-Mediated Resetting of Cellular Redox Potential and Bioenergetics

The synergy between Mycobacterium tuberculosis and human immunodeficiency virus-1 (HIV-1) interferes with therapy and facilitates the pathogenesis of both human pathogens. Fundamental mechanisms by which M. tuberculosis exacerbates HIV-1 infection are not clear. Here, we show that exosomes secreted...

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Detalles Bibliográficos
Autores principales: Tyagi, Priyanka, Pal, Virender Kumar, Agrawal, Ragini, Singh, Shalini, Srinivasan, Sandhya, Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064780/
https://www.ncbi.nlm.nih.gov/pubmed/32127457
http://dx.doi.org/10.1128/mBio.03293-19