Development and Validation of a Hydrophilic Interaction Liquid Chromatography Tandem Mass Spectrometry Method for the Determination of Asparagine in Human Serum

L-Asparagine (ASN) is the catalyze substrate of L-asparaginase (ASNase), which is an important drug for acute lymphoblastic leukemia (ALL) patients. The ASN level is found to be closely associated with the effectiveness of ASNase treatment. In this study, a hydrophilic interaction liquid chromatogra...

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Detalles Bibliográficos
Autores principales: Lu, Haoyang, Zeng, Xiaoyun, Yu, Lihua, Wang, Zhanzhang, Lin, Danna, Ni, Xiaojia, Shang, Dewei, Zhang, Ming, Hu, Jinqing, Deng, Shuhua, Zhu, Xiuqing, Chen, Yuqing, Xie, Huanshan, Yang, Lihua, Wen, Yuguan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064832/
https://www.ncbi.nlm.nih.gov/pubmed/32180807
http://dx.doi.org/10.1155/2020/6980392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064832/
https://www.ncbi.nlm.nih.gov/pubmed/32180807
http://dx.doi.org/10.1155/2020/6980392

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