HSP70 Inhibition Leads to the Activation of Proteasomal System under Mild Hyperthermia Conditions in Young and Senescent Fibroblasts

Aging has been characterized with the accumulation of oxidized proteins, as a consequence of progressive decline in proteostasis capacity. Among others, proteasomal system is an efficient protein turnover complex to avoid aggregation of oxidized proteins. Heat shock protein 70 (HSP70) is another cri...

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Detalles Bibliográficos
Autores principales: Bozaykut, Perinur, Sozen, Erdi, Kaga, Elif, Ece, Asli, Ozaltin, Esra, Bergquist, Jonas, Kartal Ozer, Nesrin, Karademir Yilmaz, Betul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064868/
https://www.ncbi.nlm.nih.gov/pubmed/32190179
http://dx.doi.org/10.1155/2020/9369524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064868/
https://www.ncbi.nlm.nih.gov/pubmed/32190179
http://dx.doi.org/10.1155/2020/9369524

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