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Extracellular vesicles derived from injured vascular tissue promote the formation of tertiary lymphoid structures in vascular allografts
Tertiary lymphoid structures (TLS) accumulate at sites of chronic injury where they function as an ectopic germinal center, fostering local autoimmune responses. Vascular injury leads to the release of endothelial‐derived apoptotic exosome‐like vesicles (ApoExo) that contribute to rejection in trans...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064890/ https://www.ncbi.nlm.nih.gov/pubmed/31729155 http://dx.doi.org/10.1111/ajt.15707 |