Decreased circulating CXCR3 + CCR9+T helper cells are associated with elevated levels of their ligands CXCL10 and CCL25 in the salivary gland of patients with Sjögren’s syndrome to facilitate their concerted migration

CCR9 + T helper (Th) cells can induce Sjögren‐like symptoms in mice and both CCR9 + Th cells and their ligand CCL25 are increased in the salivary glands of primary Sjögren's syndrome (pSS) patients. Increased circulating CCR9 + Th cells are present in pSS patients. CCR9 + Th cells are hyperresp...

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Detalles Bibliográficos
Autores principales: Blokland, Sofie L. M., Kislat, Andreas, Homey, Bernhard, Smithson, Glennda M., Kruize, Aike A., Radstake, Timothy R. D. J., van Roon, Joel A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Human Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064901/
https://www.ncbi.nlm.nih.gov/pubmed/31733111
http://dx.doi.org/10.1111/sji.12852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064901/
https://www.ncbi.nlm.nih.gov/pubmed/31733111
http://dx.doi.org/10.1111/sji.12852

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