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Chemical activation of the Piezo1 channel drives mesenchymal stem cell migration via inducing ATP release and activation of P2 receptor purinergic signaling

In this study, we examined the Ca(2+)‐permeable Piezo1 channel, a newly identified mechanosensing ion channel, in human dental pulp‐derived mesenchymal stem cells (MSCs) and hypothesized that activation of the Piezo1 channel regulates MSC migration via inducing ATP release and activation of the P2 r...

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Detalles Bibliográficos
Autores principales: Mousawi, Fatema, Peng, Hongsen, Li, Jing, Ponnambalam, Sreenivasan, Roger, Sébastien, Zhao, Hucheng, Yang, Xuebin, Jiang, Lin‐Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064961/
https://www.ncbi.nlm.nih.gov/pubmed/31746084
http://dx.doi.org/10.1002/stem.3114