A simplified method for therapeutic drug monitoring of mitotane by gas chromatography‐electron ionization‐mass spectrometry

Mitotane is a key drug for the treatment of adrenal cortical carcinoma. Due to its narrow therapeutic window, 14–20 μg/mL, monitoring its concentration is crucially important. In this study, a simplified method for measuring mitotane in plasma using gas chromatography‐electron ionization‐mass spectr...

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Detalles Bibliográficos
Autores principales: Ando, Motozumi, Hirabatake, Masaki, Yasui, Hisateru, Fukushima, Shoji, Sugioka, Nobuyuki, Hashida, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064981/
https://www.ncbi.nlm.nih.gov/pubmed/31826297
http://dx.doi.org/10.1002/bmc.4776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064981/
https://www.ncbi.nlm.nih.gov/pubmed/31826297
http://dx.doi.org/10.1002/bmc.4776

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