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A novel caged Cookson‐type reagent toward a practical vitamin D derivatization method for mass spectrometric analyses

RATIONALE: 25‐Hydroxylated vitamin D is the best marker for vitamin D (VD). Due to its low ionization efficiency, a Cookson‐type reagent, 1,2,4‐triazoline‐3,5‐dione (TAD), is used to improve the detection/quantification of VD metabolites by liquid chromatography/tandem mass spectrometry (LC/MS/MS)....

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Detalles Bibliográficos
Autores principales: Seki, Masahiko, Sato, Makoto, Takiwaki, Masaki, Takahashi, Koji, Kikutani, Yoshikuni, Satoh, Mamoru, Nomura, Fumio, Kuroda, Yutaka, Fukuzawa, Seketsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064983/
https://www.ncbi.nlm.nih.gov/pubmed/31715032
http://dx.doi.org/10.1002/rcm.8648