Catalytic Asymmetric Fluorination of Copper Carbene Complexes: Preparative Advances and a Mechanistic Rationale

The Cu‐catalyzed reaction of substituted α‐diazoesters with fluoride gives α‐fluoroesters with ee values of up to 95 %, provided that chiral indane‐derived bis(oxazoline) ligands are used that carry bulky benzyl substituents at the bridge and moderately bulky isopropyl groups on their core. The appa...

Descripción completa

Detalles Bibliográficos
Autores principales: Buchsteiner, Michael, Martinez‐Rodriguez, Luis, Jerabek, Paul, Pozo, Iago, Patzer, Michael, Nöthling, Nils, Lehmann, Christian W., Fürstner, Alois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065061/
https://www.ncbi.nlm.nih.gov/pubmed/31916634
http://dx.doi.org/10.1002/chem.202000081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065061/
https://www.ncbi.nlm.nih.gov/pubmed/31916634
http://dx.doi.org/10.1002/chem.202000081

Ejemplares similares