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NMR Characterization of Surface Receptor Protein Interactions in Live Cells Using Methylcellulose Hydrogels
Interactions of transmembrane receptors with their extracellular ligands are essential for cellular communication and signaling and are therefore a major focus in drug discovery programs. The transition from in vitro to live cell interaction studies, however, is typically a bottleneck in many drug d...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065066/ https://www.ncbi.nlm.nih.gov/pubmed/31721390 http://dx.doi.org/10.1002/anie.201913585 |