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NMR Characterization of Surface Receptor Protein Interactions in Live Cells Using Methylcellulose Hydrogels

Interactions of transmembrane receptors with their extracellular ligands are essential for cellular communication and signaling and are therefore a major focus in drug discovery programs. The transition from in vitro to live cell interaction studies, however, is typically a bottleneck in many drug d...

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Detalles Bibliográficos
Autores principales: Mateos, Borja, Sealey‐Cardona, Marco, Balazs, Katja, Konrat, Judith, Staffler, Guenther, Konrat, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065066/
https://www.ncbi.nlm.nih.gov/pubmed/31721390
http://dx.doi.org/10.1002/anie.201913585