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Putative risk alleles for LATE‐NC with hippocampal sclerosis in population‐representative autopsy cohorts

Limbic‐predominant age‐related TAR‐DNA‐binding protein‐43 (TDP‐43) encephalopathy with hippocampal sclerosis pathology (LATE‐NC + HS) is a neurodegenerative disorder characterized by severe hippocampal CA1 neuron loss and TDP‐43‐pathology, leading to cognitive dysfunction and dementia. Polymorphisms...

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Detalles Bibliográficos
Autores principales: Hokkanen, Suvi R. K., Kero, Mia, Kaivola, Karri, Hunter, Sally, Keage, Hannah A. D., Kiviharju, Anna, Raunio, Anna, Tienari, Pentti J., Paetau, Anders, Matthews, Fiona E., Fleming, Jane, Graff, Caroline, Polvikoski, Tuomo M., Myllykangas, Liisa, Brayne, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065086/
https://www.ncbi.nlm.nih.gov/pubmed/31376286
http://dx.doi.org/10.1111/bpa.12773