Upregulation of Cisd2 attenuates Alzheimer's‐related neuronal loss in mice

CDGSH iron–sulfur domain‐containing protein 2 (Cisd2), a protein that declines in an age‐dependent manner, mediates lifespan in mammals. Cisd2 deficiency causes accelerated aging and shortened lifespan, whereas persistent expression of Cisd2 promotes longevity in mice. Alzheimer's disease (AD)...

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Detalles Bibliográficos
Autores principales: Chen, Yi‐Fan, Chou, Tzu‐Yu, Lin, I‐Hsuan, Chen, Chung‐Guang, Kao, Cheng‐Heng, Huang, Guo‐Jen, Chen, Liang‐Kung, Wang, Pei‐Ning, Lin, Ching‐Po, Tsai, Ting‐Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065100/
https://www.ncbi.nlm.nih.gov/pubmed/31837018
http://dx.doi.org/10.1002/path.5374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065100/
https://www.ncbi.nlm.nih.gov/pubmed/31837018
http://dx.doi.org/10.1002/path.5374

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