NYX‐2925 induces metabotropic N‐methyl‐d‐aspartate receptor (NMDAR) signaling that enhances synaptic NMDAR and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor

N‐methyl‐d‐aspartate receptors (NMDARs) mediate both physiological and pathophysiological processes, although selective ligands lack broad clinical utility. NMDARs are composed of multiple subunits, but N‐methyl‐d‐aspartate receptor subunit 2 (GluN2) is predominately responsible for functional heter...

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Detalles Bibliográficos
Autores principales: Bowers, M. Scott, Cacheaux, Luisa P., Sahu, Srishti U., Schmidt, Mary E., Sennello, Joseph A., Leaderbrand, Katherine, Khan, M. Amin, Kroes, Roger A., Moskal, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065110/
https://www.ncbi.nlm.nih.gov/pubmed/31376158
http://dx.doi.org/10.1111/jnc.14845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065110/
https://www.ncbi.nlm.nih.gov/pubmed/31376158
http://dx.doi.org/10.1111/jnc.14845

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