Noninvasive prenatal screening for patients with high body mass index: Evaluating the impact of a customized whole genome sequencing workflow on sensitivity and residual risk

OBJECTIVE: Women with high body mass index (BMI) tend to have reduced fetal fraction (FF) during cell‐free DNA‐based noninvasive prenatal screening (NIPS), causing test failure rates up to 24.3% and prompting guidelines that recommend aneuploidy screening other than NIPS for patients with significan...

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Detalles Bibliográficos
Autores principales: Muzzey, Dale, Goldberg, James D., Haverty, Carrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065115/
https://www.ncbi.nlm.nih.gov/pubmed/31697845
http://dx.doi.org/10.1002/pd.5603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065115/
https://www.ncbi.nlm.nih.gov/pubmed/31697845
http://dx.doi.org/10.1002/pd.5603

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