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P2X7 activation enhances skeletal muscle metabolism and regeneration in SOD1G93A mouse model of amyotrophic lateral sclerosis

Muscle weakness plays an important role in neuromuscular disorders comprising amyotrophic lateral sclerosis (ALS). However, it is not established whether muscle denervation originates from the motor neurons, the muscles or more likely both. Previous studies have shown that the expression of the SOD1...

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Detalles Bibliográficos
Autores principales: Fabbrizio, Paola, Apolloni, Savina, Bianchi, Andrea, Salvatori, Illari, Valle, Cristiana, Lanzuolo, Chiara, Bendotti, Caterina, Nardo, Giovanni, Volonté, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065186/
https://www.ncbi.nlm.nih.gov/pubmed/31376190
http://dx.doi.org/10.1111/bpa.12774