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Ovarian cancer‐associated mesothelial cells induce acquired platinum‐resistance in peritoneal metastasis via the FN1/Akt signaling pathway

Peritoneal dissemination of ovarian cancer (OvCa) arises from the surface of the peritoneum, covered by monolayer of mesothelial cells (MCs). Given that both OvCa cells and MCs are present in the same peritoneal metastatic microenvironment, they may establish cell‐to‐cell crosstalk or phenotypic alt...

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Detalles Bibliográficos
Autores principales: Yoshihara, Masato, Kajiyama, Hiroaki, Yokoi, Akira, Sugiyama, Mai, Koya, Yoshihiro, Yamakita, Yoshihiko, Liu, Wenting, Nakamura, Kae, Moriyama, Yoshinori, Yasui, Hiroaki, Suzuki, Shiro, Yamamoto, Yusuke, Ricciardelli, Carmela, Nawa, Akihiro, Shibata, Kiyosumi, Kikkawa, Fumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065188/
https://www.ncbi.nlm.nih.gov/pubmed/31904865
http://dx.doi.org/10.1002/ijc.32854