Evidence that the multiflorine‐derived substituted quinazolidine 55P0251 augments insulin secretion and lowers blood glucose via antagonism at α(2)‐adrenoceptors in mice

AIMS: To investigate the mechanism of action of 55P0251, a novel multiflorine‐derived substituted quinazolidine that augments insulin release and lowers blood glucose in rodents, but does not act via mechanisms addressed by any antidiabetic agent in clinical use. MATERIALS AND METHODS: Using male mi...

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Detalles Bibliográficos
Autores principales: Lehner, Zsuzsanna, Stadlbauer, Karin, Brunmair, Barbara, Adorjan, Immanuel, Genov, Miroslav, Kautzky‐Willer, Alexandra, Scherer, Thomas, Scheinin, Mika, Bauer, Leonhardt, Fürnsinn, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065191/
https://www.ncbi.nlm.nih.gov/pubmed/31608542
http://dx.doi.org/10.1111/dom.13895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065191/
https://www.ncbi.nlm.nih.gov/pubmed/31608542
http://dx.doi.org/10.1111/dom.13895

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