Polyfunctional, Proinflammatory, Tissue‐Resident Memory Phenotype and Function of Synovial Interleukin‐17A+CD8+ T Cells in Psoriatic Arthritis

OBJECTIVE: Genetic associations imply a role for CD8+ T cells and the interleukin‐23 (IL‐23)/IL‐17 axis in psoriatic arthritis (PsA) and other spondyloarthritides (SpA). IL‐17A+CD8+ (Tc17) T cells are enriched in the synovial fluid (SF) of patients with PsA, and IL‐17A blockade is clinically efficac...

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Detalles Bibliográficos
Autores principales: Steel, Kathryn J. A., Srenathan, Ushani, Ridley, Michael, Durham, Lucy E., Wu, Shih‐Ying, Ryan, Sarah E., Hughes, Catherine D., Chan, Estee, Kirkham, Bruce W., Taams, Leonie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Psoriatic Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065207/
https://www.ncbi.nlm.nih.gov/pubmed/31677365
http://dx.doi.org/10.1002/art.41156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065207/
https://www.ncbi.nlm.nih.gov/pubmed/31677365
http://dx.doi.org/10.1002/art.41156

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