A phase 1, randomized, pharmacokinetic trial of the effect of different meal compositions, whole milk, and alcohol on cannabidiol exposure and safety in healthy subjects

OBJECTIVE: The pharmacokinetics (PK) and safety of single oral 750‐mg doses of a plant‐derived pharmaceutical formulation of highly purified cannabidiol (CBD; Epidiolex in the USA and Epidyolex in Europe; 100‐mg/mL oral solution) were assessed in healthy adults following a high‐fat/calorie meal (n =...

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Detalles Bibliográficos
Autores principales: Crockett, Julie, Critchley, David, Tayo, Bola, Berwaerts, Joris, Morrison, Gilmour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065230/
https://www.ncbi.nlm.nih.gov/pubmed/32012251
http://dx.doi.org/10.1111/epi.16419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065230/
https://www.ncbi.nlm.nih.gov/pubmed/32012251
http://dx.doi.org/10.1111/epi.16419

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