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HSV-2 Infection of Human Genital Epithelial Cells Upregulates TLR9 Expression Through the SP1/JNK Signaling Pathway

It is known that herpes simplex virus type 2 (HSV-2) triggers the activation of Toll-like receptor (TLR) 9 signaling pathway and the consequent production of antiviral cytokines in dendritic cells. However, the impact of HSV-2 infection on TLR9 expression and signaling in genital epithelial cells, t...

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Detalles Bibliográficos
Autores principales: Hu, Kai, Fu, Ming, Wang, Jun, Luo, Sukun, Barreto, Mariana, Singh, Rubin, Chowdhury, Tasnim, Li, Mei, Zhang, Mudan, Guan, Xinmeng, Xiao, Juhua, Hu, Qinxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065266/
https://www.ncbi.nlm.nih.gov/pubmed/32194565
http://dx.doi.org/10.3389/fimmu.2020.00356