Genotyping of a gene cluster for production of colibactin and in vitro genotoxicity analysis of Escherichia coli strains obtained from the Japan Collection of Microorganisms

INTRODUCTION: Colibactin is a small genotoxic molecule produced by enteric bacteria, including certain Escherichia coli (E. coli) strains harbored in the human large intestine. This polyketide-peptide genotoxin is considered to contribute to the development of colorectal cancer. The colibactin-produ...

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Detalles Bibliográficos
Autores principales: Kawanishi, Masanobu, Shimohara, Chiaki, Oda, Yoshimitsu, Hisatomi, Yuuta, Tsunematsu, Yuta, Sato, Michio, Hirayama, Yuichiro, Miyoshi, Noriyuki, Iwashita, Yuji, Yoshikawa, Yuko, Sugimura, Haruhiko, Mutoh, Michihiro, Ishikawa, Hideki, Wakabayashi, Keiji, Yagi, Takashi, Watanabe, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065307/
https://www.ncbi.nlm.nih.gov/pubmed/32175032
http://dx.doi.org/10.1186/s41021-020-00149-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065307/
https://www.ncbi.nlm.nih.gov/pubmed/32175032
http://dx.doi.org/10.1186/s41021-020-00149-z

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