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Twenty years of research on the DFS70/LEDGF autoantibody-autoantigen system: many lessons learned but still many questions
The discovery and initial characterization 20 years ago of antinuclear autoantibodies (ANAs) presenting a dense fine speckled (DFS) nuclear pattern with strong staining of mitotic chromosomes, detected by indirect immunofluorescence assay in HEp-2 cells (HEp-2 IIFA test), has transformed our view on...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065333/ https://www.ncbi.nlm.nih.gov/pubmed/32127038 http://dx.doi.org/10.1186/s13317-020-0126-4 |