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Twenty years of research on the DFS70/LEDGF autoantibody-autoantigen system: many lessons learned but still many questions

The discovery and initial characterization 20 years ago of antinuclear autoantibodies (ANAs) presenting a dense fine speckled (DFS) nuclear pattern with strong staining of mitotic chromosomes, detected by indirect immunofluorescence assay in HEp-2 cells (HEp-2 IIFA test), has transformed our view on...

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Detalles Bibliográficos
Autores principales: Ortiz-Hernandez, Greisha L., Sanchez-Hernandez, Evelyn S., Casiano, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065333/
https://www.ncbi.nlm.nih.gov/pubmed/32127038
http://dx.doi.org/10.1186/s13317-020-0126-4