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Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium

BACKGROUND: How intestinal epithelial cells interact with the microbiota and how this is regulated at the gene expression level are critical questions. Smarcad1 is a conserved chromatin remodeling factor with a poorly understood tissue function. As this factor is highly expressed in the stem and pro...

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Detalles Bibliográficos
Autores principales: Kazakevych, Juri, Denizot, Jérémy, Liebert, Anke, Portovedo, Mariana, Mosavie, Mia, Jain, Payal, Stellato, Claudia, Fraser, Claire, Corrêa, Renan Oliveira, Célestine, Marina, Mattiuz, Raphaël, Okkenhaug, Hanneke, Miller, J. Ross, Vinolo, Marco Aurélio Ramirez, Veldhoen, Marc, Varga-Weisz, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065452/
https://www.ncbi.nlm.nih.gov/pubmed/32160911
http://dx.doi.org/10.1186/s13059-020-01976-7