FTY720 Exerts Anti-Glioma Effects by Regulating the Glioma Microenvironment Through Increased CXCR4 Internalization by Glioma-Associated Microglia

Background: Glioblastoma (GBM) is one of the most malignant and aggressive primary brain tumors. The incurability of glioblastoma is heavily influenced by the glioma microenvironment. FTY720, a potent immunosuppressant, has been reported to exert anti-tumor effects in glioblastoma. However, the impa...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Xu-Dong, Ji, Juan, Xue, Teng-Fei, Sun, Yu-Qin, Guo, Ruo-Bing, Cheng, Hong, Sun, Xiu-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065571/
https://www.ncbi.nlm.nih.gov/pubmed/32194542
http://dx.doi.org/10.3389/fimmu.2020.00178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065571/
https://www.ncbi.nlm.nih.gov/pubmed/32194542
http://dx.doi.org/10.3389/fimmu.2020.00178

Ejemplares similares