mTOR Blockade by Rapamycin in Spondyloarthritis: Impact on Inflammation and New Bone Formation in vitro and in vivo

Introduction: Spondyloarthritis (SpA) is characterized by inflammation, articular bone erosions and pathologic new bone formation. Targeting TNFα or IL-17A with current available therapies reduces inflammation in SpA, however, treatment of the bone pathology in SpA remains an unmet clinical need. Ac...

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Detalles Bibliográficos
Autores principales: Chen, Sijia, van Tok, Melissa N., Knaup, Véronique L., Kraal, Lianne, Pots, Désiree, Bartels, Lina, Gravallese, Ellen M., Taurog, Joel D., van de Sande, Marleen, van Duivenvoorde, Leonie M., Baeten, Dominique L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065603/
https://www.ncbi.nlm.nih.gov/pubmed/32194539
http://dx.doi.org/10.3389/fimmu.2019.02344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065603/
https://www.ncbi.nlm.nih.gov/pubmed/32194539
http://dx.doi.org/10.3389/fimmu.2019.02344

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