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Diverse effects of interferon alpha on the establishment and reversal of HIV latency

HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4(+) T cells. Latently infected CD4(+) T cells do not express viral proteins and are therefore...

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Detalles Bibliográficos
Autores principales: Van der Sluis, Renée M., Zerbato, Jennifer M., Rhodes, Jake W., Pascoe, Rachel D., Solomon, Ajantha, Kumar, Nitasha A., Dantanarayana, Ashanti I., Tennakoon, Surekha, Dufloo, Jérémy, McMahon, James, Chang, Judy J., Evans, Vanessa A., Hertzog, Paul J., Jakobsen, Martin R., Harman, Andrew N., Lewin, Sharon R., Cameron, Paul U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065813/
https://www.ncbi.nlm.nih.gov/pubmed/32109259
http://dx.doi.org/10.1371/journal.ppat.1008151