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Reovirus uses macropinocytosis-mediated entry and fast axonal transport to infect neurons

Several barriers protect the central nervous system (CNS) from pathogen invasion. Yet viral infections of the CNS are common and often debilitating. Understanding how neurotropic viruses co-opt host machinery to overcome challenges to neuronal entry and transmission is important to combat these infe...

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Detalles Bibliográficos
Autores principales: Aravamudhan, Pavithra, Raghunathan, Krishnan, Konopka-Anstadt, Jennifer, Pathak, Amrita, Sutherland, Danica M., Carter, Bruce D., Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065821/
https://www.ncbi.nlm.nih.gov/pubmed/32109948
http://dx.doi.org/10.1371/journal.ppat.1008380