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Direct measurement of vertical forces shows correlation between mechanical activity and proteolytic ability of invadopodia
Mechanobiology plays a prominent role in cancer invasion and metastasis. The ability of a cancer to degrade extracellular matrix (ECM) is likely connected to its invasiveness. Many cancer cells form invadopodia—micrometer-sized cellular protrusions that promote invasion through matrix degradation (p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065877/ https://www.ncbi.nlm.nih.gov/pubmed/32195338 http://dx.doi.org/10.1126/sciadv.aax6912 |