Direct measurement of vertical forces shows correlation between mechanical activity and proteolytic ability of invadopodia

Mechanobiology plays a prominent role in cancer invasion and metastasis. The ability of a cancer to degrade extracellular matrix (ECM) is likely connected to its invasiveness. Many cancer cells form invadopodia—micrometer-sized cellular protrusions that promote invasion through matrix degradation (p...

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Detalles Bibliográficos
Autores principales: Dalaka, E., Kronenberg, N. M., Liehm, P., Segall, J. E., Prystowsky, M. B., Gather, M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065877/
https://www.ncbi.nlm.nih.gov/pubmed/32195338
http://dx.doi.org/10.1126/sciadv.aax6912

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