Cargando…

Tumor cell–organized fibronectin maintenance of a dormant breast cancer population

Tumors can undergo long periods of dormancy, with cancer cells entering a largely quiescent, nonproliferative state before reactivation and outgrowth. To understand the role of the extracellular matrix (ECM) in regulating tumor dormancy, we created an in vitro cell culture system with carefully cont...

Descripción completa

Detalles Bibliográficos
Autores principales: Barney, Lauren E., Hall, Christopher L., Schwartz, Alyssa D., Parks, Akia N., Sparages, Christopher, Galarza, Sualyneth, Platt, Manu O., Mercurio, Arthur M., Peyton, Shelly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065904/
https://www.ncbi.nlm.nih.gov/pubmed/32195352
http://dx.doi.org/10.1126/sciadv.aaz4157