Human RPA activates BLM’s bidirectional DNA unwinding from a nick

BLM is a multifunctional helicase that plays critical roles in maintaining genome stability. It processes distinct DNA substrates, but not nicked DNA, during many steps in DNA replication and repair. However, how BLM prepares itself for diverse functions remains elusive. Here, using a combined singl...

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Detalles Bibliográficos
Autores principales: Qin, Zhenheng, Bi, Lulu, Hou, Xi-Miao, Zhang, Siqi, Zhang, Xia, Lu, Ying, Li, Ming, Modesti, Mauro, Xi, Xu-Guang, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065910/
https://www.ncbi.nlm.nih.gov/pubmed/32101168
http://dx.doi.org/10.7554/eLife.54098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065910/
https://www.ncbi.nlm.nih.gov/pubmed/32101168
http://dx.doi.org/10.7554/eLife.54098

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