Simvastatin nanoliposome induces myocardial and hepatic toxicities due to its absorption enhancement in mice

Nanoliposome is a useful dosage form to increase solubility and absorption of simvastatin (SMV), and consequently improves its therapeutic effects. However, in vivo toxicity of SMV could also be elevated accompanied by the absorption enhancement, which is a decisive factor for the clinical applicati...

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Detalles Bibliográficos
Autores principales: Tuerdi, Nuerbiye, Anwaier, Gulinigaer, Zhang, Xing, Liu, Shu, Shen, Wanli, Liu, Wen, Shen, Qiang, Qi, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066038/
https://www.ncbi.nlm.nih.gov/pubmed/32175023
http://dx.doi.org/10.1016/j.ajps.2019.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066038/
https://www.ncbi.nlm.nih.gov/pubmed/32175023
http://dx.doi.org/10.1016/j.ajps.2019.02.002

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