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Simvastatin nanoliposome induces myocardial and hepatic toxicities due to its absorption enhancement in mice
Nanoliposome is a useful dosage form to increase solubility and absorption of simvastatin (SMV), and consequently improves its therapeutic effects. However, in vivo toxicity of SMV could also be elevated accompanied by the absorption enhancement, which is a decisive factor for the clinical applicati...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shenyang Pharmaceutical University
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066038/ https://www.ncbi.nlm.nih.gov/pubmed/32175023 http://dx.doi.org/10.1016/j.ajps.2019.02.002 |