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Redox-responsive biocompatible nanocarriers based on novel heparosan polysaccharides for intracellular anticancer drug delivery

Heparosan is a natural precursor of heparin biosynthesis in mammals. It is stable in blood circulation but can be degraded in lysosomes, showing good biocompatibility and long circulation features. So heparosan can be designed as anticancer drug carriers to increase tumor selectivity and improve the...

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Detalles Bibliográficos
Autores principales: Qiu, Lipeng, Ge, Lu, Long, Miaomiao, Mao, Jing, Ahmed, Kamel S., Shan, Xiaotian, Zhang, Huijie, Qin, Li, Lv, Guozhong, Chen, Jinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066043/
https://www.ncbi.nlm.nih.gov/pubmed/32175020
http://dx.doi.org/10.1016/j.ajps.2018.11.005