Cargando…
Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice
Reelin is a secreted protein that plays versatile roles in neuronal development and function. The strength of Reelin signaling is regulated by proteolytic processing, but its importance in vivo is not yet fully understood. Here, we generated Reelin knock-in (PA-DV KI) mice in which the key cleavage...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066138/ https://www.ncbi.nlm.nih.gov/pubmed/32161359 http://dx.doi.org/10.1038/s41598-020-61380-w |