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Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations

“Quantile-dependent expressivity” is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population. Quantile-specific offspring-parent regression slopes (β(OP)) were estimated by quantile regression for 6227 offspring-par...

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Detalles Bibliográficos
Autor principal: Williams, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066156/
https://www.ncbi.nlm.nih.gov/pubmed/32161301
http://dx.doi.org/10.1038/s41598-020-60965-9