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Downregulation of histone methyltransferase SET8 inhibits progression of hepatocellular carcinoma

The expression of lysine methyltransferase SET8, which is involved in carcinogenesis of many types of human cancers through monomethylation of histone H4 lysine 20 (H4K20), is associated with the prognosis of hepatocellular carcinoma (HCC). We performed a functional analysis for SET8 to assess its e...

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Detalles Bibliográficos
Autores principales: Wu, Jianhua, Qiao, Kuangyuan, Du, Yanming, Zhang, Xiaoyun, Cheng, Haichao, Peng, Li, Guo, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066161/
https://www.ncbi.nlm.nih.gov/pubmed/32161353
http://dx.doi.org/10.1038/s41598-020-61402-7