Autophagy Reprograms Alveolar Progenitor Cell Metabolism in Response to Lung Injury

Autophagy is a protective cellular mechanism in response to stress conditions. However, whether autophagy is required for maintenance of the alveolar epithelium is unknown. Here, we report that the loss of autophagy-related 5 (Atg5) in AT2 cells worsened bleomycin-induced lung injury. Mechanisticall...

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Detalles Bibliográficos
Autores principales: Li, Xue, Wu, Junping, Sun, Xin, Wu, Qi, Li, Yue, Li, Kuan, Zhang, Qiuyang, Li, Yu, Abel, E. Dale, Chen, Huaiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066233/
https://www.ncbi.nlm.nih.gov/pubmed/32059792
http://dx.doi.org/10.1016/j.stemcr.2020.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066233/
https://www.ncbi.nlm.nih.gov/pubmed/32059792
http://dx.doi.org/10.1016/j.stemcr.2020.01.008

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