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A drug–drug interaction study of a novel, selective urate reabsorption inhibitor dotinurad and the non-steroidal anti-inflammatory drug oxaprozin in healthy adult males

BACKGROUND: Dotinurad is a novel, selective urate reabsorption inhibitor, which reduces serum uric acid levels by inhibiting the urate transporter 1. The results of nonclinical studies indicated the possibility that the concomitant use of the non-steroidal anti-inflammatory drug oxaprozin affects th...

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Detalles Bibliográficos
Autores principales: Furihata, Kenichi, Nagasawa, Katsuaki, Hagino, Atsushi, Kumagai, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066271/
https://www.ncbi.nlm.nih.gov/pubmed/32076889
http://dx.doi.org/10.1007/s10157-020-01855-2