The effect for hyperuricemia inpatient of uric acid overproduction type or in combination with topiroxostat on the pharmacokinetics, pharmacodynamics and safety of dotinurad, a selective urate reabsorption inhibitor

BACKGROUND: Dotinurad, a novel selective urate reabsorption inhibitor (SURI), increases urinary uric acid excretion. The aim of this study is to examine the pharmacokinetics, pharmacodynamics, and safety of dotinurad according to the type of hyperuricemia, with or without concomitant use of xanthine...

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Detalles Bibliográficos
Autores principales: Okui, Daisuke, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066310/
https://www.ncbi.nlm.nih.gov/pubmed/31734820
http://dx.doi.org/10.1007/s10157-019-01817-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066310/
https://www.ncbi.nlm.nih.gov/pubmed/31734820
http://dx.doi.org/10.1007/s10157-019-01817-3

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