Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: an exploratory, randomized, multicenter, double-blind, placebo-controlled, parallel-group early phase 2 study

BACKGROUND: Dotinurad, a novel selective urate reabsorption inhibitor (SURI) that has a future potential for the treatment of hyperuricemia, reduces serum uric acid levels by selectively inhibiting urate transporter 1 (URAT1). We evaluated the efficacy and safety of dotinurad in hyperuricemic Japane...

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Detalles Bibliográficos
Autores principales: Hosoya, Tatsuo, Sano, Takafumi, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066315/
https://www.ncbi.nlm.nih.gov/pubmed/31754882
http://dx.doi.org/10.1007/s10157-019-01802-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066315/
https://www.ncbi.nlm.nih.gov/pubmed/31754882
http://dx.doi.org/10.1007/s10157-019-01802-w

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