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The novel GLP‐1/GIP analogue DA5‐CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD

INTRODUCTION: Alzheimer's disease (AD) is the most common progressive neurodegenerative disease for which there is no cure. Recent studies have shown a close link between type 2 diabetes and AD, which suggested that drugs for type 2 diabetes may be effective for AD. GLP‐1 and GIP are incretin h...

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Detalles Bibliográficos
Autores principales: Li, Cheng, Liu, Weizhen, Li, Xiaohui, Zhang, Zijuan, Qi, Huaxin, Liu, Shijin, Yan, Ningning, Xing, Ying, Hölscher, Christian, Wang, Zhiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066337/
https://www.ncbi.nlm.nih.gov/pubmed/31960630
http://dx.doi.org/10.1002/brb3.1505